Functional Exposed Amino Acids of LamB as a vaccine candidate for Vibriosis

Functional Exposed Amino Acids of LamB as a vaccine candidate for Vibriosis

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سال انتشار:1395
چکیده
Vibriosis is one of the most serious infectious diseases in fish and shellfish. However, due to the diversity of pathogens and their complicated serotypes, the progress in vaccine development against Vibriosis has been slow. LamB proteins (or maltoporins) are a family of OMPs. It forms a betabarrel composed of three monomers and ensures the transport of maltose and maltodextrin in Gram-negative bacteria reported that recombinant Aeromonas hydrophila outer membrane protein 48, which belongs to the maltoporin group of porins, induces a protective immune response against A. hydrophila and E. tarda. Findings indicated that antibodies against LamB were protective, making this antigen a likely candidate for a…